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Keywords macrophage perivascular CAF heme oxygenase-1 stem-like CD8+ T cells CXCR4 CXCL12 tumor microenvironment chemotherapy and cancer Introduction The perivascular (Pv) niche is a dynamic tumor microenvironment (TME) composed of spatially organized immune and mesenchymal cell populations1,2,3 whose interactions influence cancer progression and therapeutic response.4,5,6,7,8,9 Pv tumor-associated macrophages (PvTAMs)4 are a central cellular component of the Pv niche, and they have been...
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.