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Doste Mamand

As seen in: BioRxiv
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Articles

Differential Modulation of JAK/STAT3 Signaling and BCL-2 Family Proteins by Tetracycline Analogues in Leukemia Models

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By Doste Mamand, Zienab M. Hassan, Hoda W. El- Gawly
| preprints.org
Submitted: 18 February 2026 You are already at the latest version Drug repurposing offers a time- and cost-efficient strategy for accelerating the development of anticancer therapies by leveraging the established safety profiles of existing pharmaceuticals.
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Novel endogenous engineering platform for robust loading and delivery of functional mRNA by extracellular vesicles

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By Antje Maria Zickler, Xiuming Liang, Dhanu Gupta, Doste Mamand
| BioRxiv
Abstract Messenger RNA (mRNA) has emerged as an attractive therapeutic molecule for a plethora of clinical applications. For in vivo functionality, mRNA therapeutics require encapsulation into effective, stable, and safe delivery systems to protect the cargo from degradation and reduce immunogenicity.
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