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Douglas PS

As seen in: Oxford University Press (OUP), PeerJ
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Articles by Douglas PS

Diagnostic Strategies for the Assessment of Suspected Stable Coronary Artery Disease : A Systematic Review and Meta-analysis

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By Biondi-Zoccai G, Douglas PS, D'Amario D
| ncbi.nlm.nih.gov
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Branched-Chain Amino Acids in Computed Tomography-Defined Adipose Depots and Coronary Artery Disease: A PROMISE Trial Biomarker Substudy

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By Ginsburg GS, Douglas PS, Giamberardino SN, Pagidipati NJ
| ncbi.nlm.nih.gov
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Influence of Obesity on Coronary Artery Disease and Clinical Outcomes in the ADVANCE Registry

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By Douglas PS, Rymer JA, Koweek LM, Duran JM
| ncbi.nlm.nih.gov
doi: 10.1161/CIRCIMAGING.122.014850. Affiliations Affiliations 1 Vanderbilt University Medical Center, Nashville, TN (A.L.). 2 HeartFlow, Redwood City, CA (N.N., C.R., S.M., J.L.). 3 St. Paul's Hospital, Radiology, Vancouver, Canada (H.T.). 4 Duke University Medical Center, Duke Clinical Research Institute, Durham, NC (J.A.R., L.M.K., P.S.D., J. M. D., M.R.P., M.A.D.). 5 Loyola University Medical Center, Maywood, IL (M.R.). 6 Centro Cardiologico Monzino, IRCCS, Milan, Italy (G.P.).
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Clinical characteristics and prognosis differences between isolated right and left ventricular myocardial infarction in the Chinese population: a retrospective study

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By Douglas PS, Crystal GJ, Jacoby RM, Casey DE
| PeerJ
Additional Information and Declarations Competing Interests The authors declare that they have no competing interests. Author Contributions Yuanyuan Chen performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the article, and approved the final draft. Chunyan Weng performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the article, and approved the final draft.
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Multimodality cardiac imaging in the 21st century: evolution, advances and future opportunities for innovation | The British Journal of Radiology

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By Douglas PS, Hlatky MA, Norgaard BL
| birpublications.org
1. Hung J, , Lang R, , Flachskampf F, , Shernan SK, , McCulloch ML, , Adams DB, , et al.. 3D echocardiography: a review of the current status and future directions. J Am Soc Echocardiogr 2007; 20: 213–33. doi: https://doi.org/10.1016/j.echo.2007.01.010 http://www.ncbi.nlm.nih.gov/pubmed/17336747 2. Dorosz JL, , Lezotte DC, , Weitzenkamp DA, , Allen LA, , Salcedo EE.
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Functional cardiac CT–Going beyond Anatomical Evaluation of Coronary Artery Disease with Cine CT, CT-FFR, CT Perfusion and Machine Learning | The British Journal of Radiology

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By Douglas PS, Hlatky MA, Norgaard BL
| birpublications.org
1. Agatston AS, , Janowitz WR, , Hildner FJ, , Zusmer NR, , Viamonte M, , Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 1990; 15: 827–32. doi: https://doi.org/10.1016/0735-1097(90)90282-T 2. Xie X, , Zhao Y, , De Bock GH, , De Jong PA, , Mali WP, , Oudkerk M, , et al.. Validation and prognosis of coronary artery calcium scoring in nontriggered thoracic computed tomography: systematic review and meta-analysis.
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Prevalence of obstructive coronary artery disease and prognosis in patients with stable symptoms and a zero-coronary calcium score

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By Newby DE, Douglas PS, Mark DB, Tracy QC
| Oxford University Press (OUP)
Computed tomography has become a cost-effective, mainstream technique for excluding coronary artery disease (CAD) in patients with stable symptoms.1–3 Non-contrast CT calcium scoring (CTCS) allows detection and quantification of coronary artery calcification (CAC), but CT coronary angiogram (CTCA) is required for imaging of calcified and non-calcified plaques as well as quantification of luminal stenoses.4 Often both techniques are performed sequentially.
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Plasma concentration of serotonin is a novel biomarker for coronary microvascular dysfunction in patients with suspected angina and unobstructive coronary arteries | European Heart Journal | Oxford Academic

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By Douglas PS, Kelsey SF, Tosoh Corp, Alexander BJr
| Oxford University Press (OUP)
It has been reported that up to 40% of patients undergoing diagnostic coronary angiography for typical chest pain have no significant coronary stenosis.1 The Women’s Ischaemia Syndrome Evaluation study showed that there are at least 3–4 million patients in the USA alone who have signs and symptoms of myocardial ischaemia despite no evidence of obstructive coronary artery disease (CAD), associated with poor quality of life, psychological distress, and health-care costs that approximate those...
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Coronary microcirculatory pathophysiology: can we afford it to remain a black box?

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By Deutsches Herzzentrum Berlin, Douglas PS, Kelsey SF, Mohammed SF
| Oxford University Press (OUP)
About 50 years ago, Likoff et al.
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Left atrial function index predicts long-term survival in stable outpatients with systolic heart failure

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By Douglas PS, Vicente Simões, Lee RJ
| Oxford University Press (OUP)
Heart failure (HF) is defined as the inability of the heart to meet the oxygen demand of metabolizing tissues.1 HF with reduced left ventricular ejection fraction (HFrEF) is primarily defined by a decrease in left ventricular (LV) systolic function, although concomitant diastolic dysfunction is common. The atrial contribution to LV filling is ?35%.2 The early stages of HF show an increased atrial response with increased reservoir and pump function.
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Fractional flow reserve by computerized tomography and subsequent coronary revascularization

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By Douglas PS, Mark DB, René R. Sevag, Thomson LE
| Oxford University Press (OUP)
Previous observations demonstrated the need for improved risk stratification and increased yield of patients who undergo invasive coronary angiography and subsequent revascularization.1 Mounting evidence over recent years supports the use of coronary computerized tomography angiography (coronary CTA) as an attractive non-invasive approach that may fulfil this gatekeeper role.2,3 However, coronary artery calcium (CAC) significantly reduces the diagnostic specificity4,5 and overall accuracy6 of...
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Sustained favourable haemodynamics 1 year after TAVI: improvement in NYHA functional class related to improvement of left ventricular diastolic function | European Heart Journal - Cardiovascular Imaging | Oxford Academic

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By Nina Ajmone, Ghulam Ali, Douglas PS, Stewart WJ
| Oxford University Press (OUP)
In the last decade, transcatheter aortic valve implantation (TAVI) has shown to be a feasible and effective therapeutic alternative in patients with symptomatic severe aortic stenosis (AS) and contraindications or high risk for surgical aortic valve replacement.1–3 Several studies have shown excellent, sustained transvalvular haemodynamics post-TAVI, together with a significant improvement in symptoms and quality of life.4–6 However, the impact of TAVI on left ventricular (LV) systolic and...
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Mitral valve and mitral valve disease

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By Gordon SPF, Douglas PS
| Oxford University Press (OUP)
The mitral valve separates the left atrium from the left ventricle (LV) and, as such, is an integral part of the high-pressure systemic circulation. Therefore, any pathology of the valve can have critical physiological effects that the anaesthetist must be aware of. Anaesthesia alters the way in which the heart, valve, and circulation interact and control of these changes needs to be both understood and anticipated.
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