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A scalable purification strategy for removal of dsRNA byproducts following IVT RNA production

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By Nathaniel E. Clark, Downstream Scientist
| insights.bio
This webinar will outline a scalable and efficient affinity solution for removal of double-stranded RNA (dsRNA) from RNA produced via in vitro transcription (IVT). This includes mRNA, circular RNA, self-amplifying RNA, and trans-amplifying RNA. dsRNA byproducts are large, highly immunogenic, and cannot be removed with common bioprocessing steps such as TFF, or olig-dT affinity chromatography.
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