Eloise Watson

Main text We read with interest the article by Lopez Sanchez and colleagues, examining the epidemiology and risk of vision loss in Leber hereditary optic neuropathy (LHON) in Australia through review of a national clinical register. 1 Lopez Sanchez M.I.G. Kearns L.S. Staffieri S.E. Clarke L. McGuinness M.B. Meteoukki W. Samuel S. Ruddle J.B. Chen C. Fraser C.L. et al. Establishing risk of vision loss in Leber hereditary optic neuropathy.

The presentations for mitochondrial diseases is highly variable and diagnosis can be challenging, even for specialist clinicians. With limited teaching and awareness of mitochondrial diseases, it is important that mitochondrial diseases can be recognised on the frontline. CLINICAL VIGNETTE A 48-year-old lady presents to you describing “missing” parts of her vision with preserved central acuity, which has been gradually getting worse over several months.