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Dudsadee Mesiri

As seen in: Nature
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Articles

Gastric mucosal brushing enhances gastric microbiome profiling compared with conventional biopsy in gastric cancer

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By Thanrada Vimonsuntirungsri, Chatpol Samuthpongtorn, Pisit Tangkijvanich, Chadin Tharavej, Thitiporn Chobarporn, Rapat Pittayanon, Dudsadee Mesiri
| Nature Verified
Abstract Gastric microbiota dysbiosis has been implicated in gastric carcinogenesis; however, the specific sampling method for assessing non-Helicobacter pylori microbiota associated with gastric cancer (GC) remains unestablished. This study compared gastric mucosal brushing with conventional biopsy for microbiota profiling in patients with GC and controls. We enrolled treatment-naïve GC patients and controls and analysed paired brushing and biopsy specimens using 16 S rRNA sequencing.
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