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Articles

Nanoscale organization is changed in native, surface AMPARs by mouse brain region and tauopathy

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By Rohit M Vaidya, Jiahao Zhang, Duncan Lee Nall, Yongjae Lee
| biorxiv.org
Abstract Synaptic AMPA receptors (AMPARs) on neuronal plasma membranes are correlated with learning and memory. Using a unique labeling and super-resolution imaging, we have visualized the nanoscale synaptic and extra-synaptic organization of native surface AMPARs for the first time in mouse brain slices as a function of brain region and tauopathy.
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Synapses without tension fail to fire in an in vitro network of hippocampal neurons.

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By Bashar Emon, Ki Yun Lee, Duncan Lee Nall, Alexandra Barishman
| biorxiv.org
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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