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Duncan Yi-Te Wan on Muck Rack

Duncan Yi-Te Wan

As seen in: BioRxiv
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Articles

Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient

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By Thang Le, Ko-Chen Chen, Duncan Yi-Te Wan, Sebastian Rui-Gu Yan
| BioRxiv
Abstract Intratumoral heterogeneity is intrinsically comprised of molecular alterations of tumor cells and extrinsically from interconnections with microenvironments. This study explores the spatial heterogeneity of ovarian clear cell carcinoma (OCCC), a rare cancer with significance to East Asian women. We profiled 21 tumors from matched ovarian and metastatic sites with spatial transcriptomic (ST) platforms including GeoMx and Visium CytAssist.
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