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Durrington PN

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An update on the first recorded case of familial hypercholesterolaemia: The Charioteer of Delphi

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By Durrington PN, Paul Durrington
| ncbi.nlm.nih.gov
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Severe Hypertriglyceridaemia and Chylomicronaemia Syndrome-Causes, Clinical Presentation, and Therapeutic Options

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By Ho JH, Wierzbicki AS, Durrington PN
| ncbi.nlm.nih.gov
Figure 1 ( a ) Dietary TGs and cholesterol are hydrolysed by lingual, gastric, pancreatic,… Figure 1 (a) Dietary TGs and cholesterol are hydrolysed by lingual, gastric, pancreatic, and intestinal lipases into free fatty acids (FFA) and glycerol that are transported from the intestinal lumen to enterocytes where they are re-esterified and packaged into the transport cargo, chylomicrons. These enter circulation via the lymphatic system (the thoracic duct) and, thence, to the subclavian vein.
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Triglycerides are more important in atherosclerosis than epidemiology has suggested.

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By Durrington PN
| ncbi.nlm.nih.gov
Epidemiology call be a useful guide to risk prediction. If, for example, the value of serum cholesterol, high density lipoprotein (HDL) cholesterol and triglycerides as predictors of future CHD events is considered, then generally the triglyceride level measured on a single occasion will add little to the prognostic information contained in cholesterol and HDL cholesterol.
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