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sAPPα Inhibits Neurite Outgrowth in Primary Mouse Neurons via GABA B Receptor Subunit 1a
amyloid precursor protein GABA receptor mouse primary neurons neurite outgrowth Significance Statement Amyloid precursor protein (APP) plays a central role in Alzheimer's disease, yet its normal functions are not fully understood. In this study, we uncover a previously unrecognized role of the GABA B Receptor in mediating the inhibitory effects of sAPPα on neurite outgrowth.
Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks
Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks† Light-based patterning of synthetic and biological hydrogels enables precise spatial and temporal control over the formation of chemical bonds. However, photoinitiators are typically used to generate free radicals, which are detrimental to human cells.
Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks
Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks† Light-based patterning of synthetic and biological hydrogels enables precise spatial and temporal control over the formation of chemical bonds. However, photoinitiators are typically used to generate free radicals, which are detrimental to human cells.
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