Integrating optical imaging techniques with cancer-specific molecular imaging agents offers a promising avenue for enhancing endoscopic cancer detection and resection [1]. White light endoscopy remains the predominant method for visualizing, biopsying, and locally resecting cancers in the gastrointestinal and urinary tract. Nevertheless, it is not without its limitations, notably its suboptimal performance in detecting multifocal and flat tumors and in delineating tumor boundaries.