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T. Wang et al., Brain displacement and nonlinear deformation following human spaceflight. Proc. Natl. Acad. Sci. U.S.A. 123, e2505682122 (2026). G. A. Palmer et al., Reproductive biomedicine in space: Implications for gametogenesis, fertility and ethical considerations in the era of commercial spaceflight. Reprod. BioMed. Online 105431 (2026). E.
Low-capacity runner (LCR) and high-capacity runner (HCR) rat strains are divergent for running capacity and aerobic fitness. The LCR rats are susceptible to obesity, insulin resistance, and fatty liver whereas the HCR are protected. We performed studies testing the hypothesis that the divergence in susceptibility for obesity and metabolic dysfunction between HCR/LCR is due to differences in hepatic mitochondrial function that also may drive differences in energy expenditure and substrate usage.
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