Articles by e smith
What Oncology Fellowship Is Really Like: Jonathan Lee, MD and Chinmay Jani, MD
In this episode of The Moonlight Shift, Gina Mauro sits down with two rising stars in hematology-oncology at the same terrifying threshold: the end of fellowship and the beginning of independent practice.
Ateganosine Combo Demonstrates Disease Control in Third-Line NSCLC
Ateganosine (THIO) followed by cemiplimab (Libtayo) produced disease control in patients with third-line advanced non–small cell lung cancer (NSCLC), according to a news release from MAIA Biotechnology on initial efficacy data from Part C of the phase 2 THIO-101 trial (NCT05208944).¹ What did the THIO-101 Part C data show? In the Part C expansion phase of the study, patients received ateganosine followed by cemiplimab in 21-day cycles.
All-Oral Decitabine/Cedazuridine Combo Enters Frontline AML
Following a Frontline Forum program, Amer Zeidan, MBBS, MD, discussed the May 2026 FDA approval of all-oral decitabine/cedazuridine (DEC-C; Inqovi) plus venetoclax (Venclexta) for newly diagnosed acute myeloid leukemia (AML) and how quickly it may replace injectable hypomethylating agent (HMA) combinations.1 The approval was based on the phase 2 ASCERTAIN-V trial (NCT04657081).2 Topline data at the time of the approval showed that DEC-C plus venetoclax produced complete responses (CRs) in...
HARMONi-6: Evaluating the Safety and Generalizability of Ivonescimab in NSCLC
The therapeutic landscape for non–small cell lung cancer (NSCLC) is shifting with the introduction of ivonescimab (SMT112), a novel PD-1 and VEGF-targeted bispecific antibody.
18 Advanced Oncoplastic Breast Surgery Using Multiple Pedicles Following Breast-Conserving Surgery: Oncologic and Surgical Outcomes
Background Oncoplastic breast surgery (OPS) is a form of breast conservation surgery (BCS) that has been shown to be a safe and effective treatment for breast cancer. OPS includes both volume displacement and volume replacement techniques, which allow for oncologic resection while preserving aesthetic outcomes. This study aims to evaluate advanced oncoplastic approaches that combine oncoplastic approaches using multiple pedicles and techniques to address complex reconstructive needs following BCS.
E Smith | Authors | CancerNetwork
Targeted axillary dissection with sentinel lymph node biopsy successfully retrieved all preoperatively identified positive nodes in node-positive breast cancer patients treated with neoadjuvant chemotherapy, with no axillary recurrences observed.
19 Targeted Axillary Dissection—Does the Biopsy-Proven Node Need to Be Localized? A Retrospective Review of Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Systemic Therapy
Introduction Optimal axillary management for patients with initially node-positive breast cancer treated with neoadjuvant chemotherapy (NACT) remains controversial. Sentinel lymph node biopsy (SLNB) in this setting is increasingly being used to reduce surgical morbidity, but concerns persist regarding nodal staging accuracy and recurrence risk. Targeted axillary dissection (TAD) has been proposed to improve staging by ensuring the removal of the clipped metastatic node.
Mechanisms of carbon dioxide detection in the earthworm Dendrobaena veneta.
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How Orthotics Burlington Can Improve The Movement of Your Feet?
Orthotics, also called arch supports or embeds, are used to help people with foot pain. Orthotics can be an extremely amazing approach to change the way that we walk, and keep joints in the arrangement. The mix of foot changes and orthotic treatment guarantees that you heal sooner and arrive at your maximum capacity quicker than with orthotic treatment alone regardless of whether your condition is persistent and of a difficult sort.
3 Types of Foot And Ankle Pain You Shouldn't Ignore
If you are suffering from foot pain, it's essential to see a specialist for a checkup. Foot pain can be trouble, and research has shown it can influence a person's mindset and life. Eventually, you have the right to feel well and return to your normal life, and with the correct treatment plan from Optimal Ankle, you can. So, here are various types of foot and ankle pain you should not ignore. Osteoarthritis Osteoarthritis is the breakdown of ligaments in a joint.
Abstract 10000: Mutation in CELA2A Derives Early-onset Cardiovascular Diseases
Abstract Introduction: Metabolic syndrome (MetS) is a cluster of inherited metabolic risk factors that increase the predisposition to Coronary artery disease (CAD). Genetic factors that underlie the association of MetS risk factors are not understood. Earlier genetic studies of outlier families have shown that the extreme forms of the disease can be caused by single gene mutations.
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