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Eain A. Murphy on Muck Rack

Eain A. Murphy

As seen in: BioRxiv
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Articles

Protein-S-Nitrosylation of Human Cytomegalovirus pp65 Reduces its Ability to Undermine cGAS.

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By Justin Cox, Masatoshi Nukui, Eain A. Murphy
| BioRxiv
Abstract Post-translational modifications (PTMs) are key regulators of various processes important for cell survival. These modifications are critical for dealing with stress conditions such as those observed in disease states and during infections with various pathogens.
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Herpes Simplex Virus-1 targets the 2’-3’cGAMP importer SLC19A1 as an antiviral countermeasure.

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By Zsuzsa K Szemere, Eain A. Murphy
| BioRxiv
Abstract To establish a successful infection, herpes simplex virus-1 (HSV-1), a virus with high seropositivity in the human population, must undermine host innate and intrinsic immune defense mechanisms, including the stimulator of interferon genes (STING) pathway.
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