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Eda Isil Altiok on Muck Rack

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Multivalent Conjugates of Basic Fibroblast Growth Factor Enhances In Vitro Proliferation and Migration of Endothelial Cells

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By Aline Zbinden, Shane Browne, Eda Isil Altiok, Felicia Svedlund
| Royal Society of Chemistry Verified
Growth factors hold great promise for regenerative therapies. However, their clinical use has been halted by poor efficacy and rapid clearance from tissue, necessitating the delivery of extremely high doses to achieve clinical effectiveness which raises safety concerns. Thus, strategies to either enhance growth factor activity at low doses or to increase their residence time within target tissues are necessary for clinical success.
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