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Histopathological Correlates of Global and Segmental Left Ventricular Systolic Dysfunction in Experimental Chronic Chagas Cardiomyopathy

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By Jorge Mejia Cabeza, Hélio Cesar Salgado, Rubens Fazan Júnior, Benedito Carlos Maciel, Edécio Cunha‐Neto, José Antônio Marin‐Neto
| jaha.ahajournals.org
Background Chronic Chagas cardiomyopathy in humans is characterized by segmental left ventricular wall motion abnormalities (WMA), mainly in the early stages of disease. This study aimed at investigating the detection of WMA and its correlation with the underlying histopathological changes in a chronic Chagas cardiomyopathy model in hamsters.
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