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Edinburgh BioQuarter Edinburgh

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Hijacking homeostasis: Regulation of the tumor microenvironment by apoptosis

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By Christopher Gregory, Edinburgh BioQuarter Edinburgh
| Wiley Online Library
3.2.1 Macrophage efferocytosis and its implications for the TME: The “3Rs” of apoptosis Efferocytosis is essential to the homeostatic value of apoptosis (reviewed by8, 98, 154, 236-238 and, as alluded to already, many of the changes at the apoptotic cell surface have proven utility in coupling with receptors on macrophages (as well as on other, “non-professional” efferocytes) in recognition of the dying cell.
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