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Edouard G. Stanley on Muck Rack

Edouard G. Stanley

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Articles

Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells - Nature Biotechnology

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By Elizabeth S. Ng, Ritika Saxena, Shicheng Sun, Sandra Capellera-Garcia, Feiyang Ma, Mirana Ramialison, Edouard G. Stanley
| Nature Verified
Abstract Hematopoietic stem cells (HSCs) derived from human induced pluripotent stem cells (iPS cells) have important biomedical applications. We identified differentiation conditions that generate HSCs defined by robust long-term multilineage engraftment in immune-deficient NOD,B6.Prkdcscid Il2rgtm1Wjl/SzJ KitW41/W41 mice.
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Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

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By Christine Wells, Ali Motazedian, Edouard G. Stanley, Freya F. Bruveris
| Nature Verified
Abstract Defining the ontogeny of the human adaptive immune system during embryogenesis has implications for understanding childhood diseases including leukaemias and autoimmune conditions. Using RAG1:GFP human pluripotent stem cell reporter lines, we examined human T-cell genesis from pluripotent-stem-cell-derived haematopoietic organoids.
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