Eduarda Ribeiro Braga

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4. Discussion The detection of serogroups using MAT is dependent on the phase of the infection being investigated [1]. During the first phase of infection, low antibody titers against common antigens of Leptospira spp. and the cross-reactivity of serogroups are typical [1]. Titers of 1:100 or 1:200 may suggest an early stage of infection or residual antibodies from previous infections, while high titers are more common in recent or acute infections [36].