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Edward Robert Wassman on Muck Rack

Edward Robert Wassman

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The Arduous Path to Drug Approval for the Management of Prader-Willi Syndrome: A Historical Perspective and Call to Action

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By Deepan Singh, Jennifer Miller, Merlin G. Butler, Edward Robert Wassman
| MDPI
Prader–Willi syndrome (PWS) is a neuroendocrine genetic disorder resulting from the loss of paternally expressed imprinted genes in chromosome 15q11-q13 [1,2]. Although characterized most prominently by life-threatening hyperphagia and obesity, PWS can also be accompanied by a multitude of other issues, including growth and other hormone deficiencies, behavioral problems, skin picking, abnormal body composition [3,4], and sleep disruption [5,6].
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