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Efstathios L. Pavlidis on Muck Rack

Efstathios L. Pavlidis

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Articles

Revolutionizing Heart Valve Therapy: A Translational Framework for Combining Decellularized Scaffolds With Genetic Modification

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By Nikolaos P. Tzavellas, Natalia Atzemoglou, Efstathios L. Pavlidis, Alkinoos Nikolis
| Wiley Online Library Verified
1 Introduction Valvular heart disease (VHD) represents a major global public health challenge, predominantly affecting the elderly and significantly contributing to cardiovascular morbidity and mortality worldwide [1]. The most prevalent conditions—aortic stenosis (AS), mitral regurgitation (MR), and aortic regurgitation (AR)—account for substantial disease burden, with aortic valve diseases responsible for approximately 61% of VHD-related deaths [2].
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