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Articles

CRISPR/Cas9 Mutagenesis in Phlebotomus papatasi: the Immune Deficiency Pathway Impacts Vector Competence for Leishmania major

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By Isabelle Louradour, Kashinath Ghosh, Ehud Inbar
| asm.org
Research Article | Host-Microbe Biology Isabelle Louradour, Kashinath Ghosh, Ehud Inbar, David L. Sacks Christian Tschudi, Editor DOI: 10.1128/mBio.01941-19 ABSTRACT Sand flies are the natural vectors for the Leishmania species that produce a spectrum of diseases in their mammalian hosts, including humans. Studies of sand fly/Leishmania interactions have been limited by the absence of genome editing techniques applicable to these insects.
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