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Ekram Hossan

As seen in: Nature, PLOS ONE
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Articles

Structure-guided design and dynamic evaluation of VP4-targeting siRNAs against rotavirus A

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By Abu Ahmed, A. Rahman, Mohammad Nazmus Sakib, Ekram Hossan, Arittra Bhattacharjee, Zeshan Mahmud Chowdhury, Jahirul Islam, Mohammad Hossain, Khaleda Jahan Satu, S. M. Sajid Hasan, Ziaul Faruque Joy
| Nature Verified
Abstract Rotavirus is a major cause of severe diarrheal disease in children under the age of five, particularly in low- and middle-income countries, with no currently available antiviral therapeutics and treatment being largely supportive. In this study, we developed an integrative in silico approach to design and evaluate siRNAs targeting conserved mRNA transcript of the VP4 gene of Rotavirus A across six geographically diverse countries.
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Cheminformatics-based screening and evaluation of phytochemicals as CDK2 inhibitors in colorectal cancer therapy

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By Nowshin Tabassum, Bioinformatics Laboratory, Noakhali Science, Ekram Hossan
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Tabassum N, Hossan ME, Islam MM, Hasan M, Islam MS, Masud S, et al. (2025) Cheminformatics-based screening and evaluation of phytochemicals as CDK2 inhibitors in colorectal cancer therapy. PLoS One 20(9): e0331438. https://doi.org/10.1371/journal.pone.0331438 Editor: Ahmed A. Al-Karmalawy, University of Mashreq, IRAQ Received: July 19, 2025; Accepted: August 17, 2025; Published: September 3, 2025 Copyright: © 2025 Tabassum et al.
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