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Elaine Santos Lima on Muck Rack

Elaine Santos Lima

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Diagnostic validity of ELISA-IgM, DPP ® rapid test, and MAT for leptospirosis diagnosis in Brazilian reference laboratories: a latent class analysis

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By Tiago Silveira Gontijo, Fabiano Borges Figueiredo, Heber Pena, Alexsandro Galdino, Ilana Teruszkin Balassiano, Vinicius Belo, Vinícius Silva Belo, Isadora Braga Gandra, Lidsy Ximenes Fonseca, Roberta Morozetti Blanco, Max Assunção Correia, Cintya de Oliveira Souza, Elaine Santos Lima
| Nature Verified
Abstract Diagnosing leptospirosis and assessing test accuracy are challenging because no single method can reliably identify true infection across all stages, thereby preventing the establishment of a definitive gold standard. This study analyzes the performance of ELISA-IgM, DPP® Leptospirosis rapid test, and MAT using Latent Class Analysis (LCA) to infer infection status in the absence of an absolute reference standard.
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