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Elena Abarinov on Muck Rack

Elena Abarinov

As seen in: BioRxiv
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Articles

Independent control of neurogenesis and dorsoventral patterning by NKX2-2

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By Sumin Jang, Hynek Wichterle, Julie Dobkin, Elena Abarinov
| BioRxiv
Abstract Human neurogenesis is disproportionately protracted, lasting >10 times longer than in mouse, allowing neural progenitors to undergo more rounds of self-renewing cell divisions and generate larger neuronal populations. In the human spinal cord, expansion of the motor neuron lineage is achieved through a newly evolved progenitor domain called vpMN (ventral motor neuron progenitor) that uniquely extends and expands motor neurogenesis.
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