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Elena Barbara Riel on Muck Rack

Elena Barbara Riel

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Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels - Nature Communications

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By Berke Türkaydin, Marcus Schewe, Elena Barbara Riel, Friederike Schulz, Johann Biedermann, Thomas Baukrowitz
| Nature Verified
Abstract The two-pore domain potassium (K2P) channels TREK-1 and TREK-2 link neuronal excitability to a variety of stimuli including mechanical force, lipids, temperature and phosphorylation. This regulation involves the C-terminus as a polymodal stimulus sensor and the selectivity filter (SF) as channel gate.
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