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Extracellular vesicles secreted by adenomyosis endometrial organoids contain miRNAs involved in adenomyosis progression, embryo implantation failure, and pregnancy complications
Research question Do extracellular vesicles (EVs) secreted by the endometrium of women with adenomyosis contain miRNAs involved in adenomyosis-related infertility? Design This is a descriptive study using organoids from eutopic endometrium of women with adenomyosis (n=4) generated and differentiated to secretory and gestational phases, in which miRNA cargo from EVs secreted by these differentiated organoids in each phase was analyzed by next generation sequencing.
Improved Models of Human Endometrial Organoids Based on Hydrogels from Decellularized Endometrium
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