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Elham Barazeghi on Muck Rack

Elham Barazeghi

As seen in: BioRxiv
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Articles

A single-cell transcriptomic comparison between small intestinal neuroendocrine tumors and their progenitor

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By Fredrik Axling, Per Hellman, Olov Norlén, Elham Barazeghi
| BioRxiv
Abstract Several studies have attempted to find the initiating drivers of small intestinal neuroendocrine tumors (SI-NET) development and the molecular mechanisms driving progression and metastatic spread. For gene expression studies using bulk microarrays and RNA sequencing, researchers commonly use normal intestinal mucosa as a control. The intestine is made up of several different cell types, and using bulk RNA-seq may generate findings that reflect factors other than the tumor transformation.
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