Elias Lahham

Patients with idiopathic refractory hypothyroidism who have been identified with oral levothyroxine resistance may benefit from IV levothyroxine as it can alleviate their symptoms and assist physicians in differentiating between true and pseudo-malabsorptive hypothyroidism after excluding any other potential causes. 1 Introduction To restore normal thyroid hormone levels in hypothyroidism, oral levothyroxine sodium (LT4) continues to be the cornerstone of treatment.