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Neoadjuvant palbociclib and endocrine therapy versus chemotherapy in ER + /HER2- breast cancer: a randomized phase II trial
Abstract In PREDIX LumB patients with estrogen receptor positive and human epidermal growth factor receptor negative (ER + /HER2-) breast cancer > 20 mm and/or with lymph node metastasis were randomized 1:1 to receive either paclitaxel weekly for 12 weeks followed by palbociclib and endocrine therapy for 12 weeks (arm A), or the reverse sequence (arm B).
IJMS | Free Full-Text | A Swedish Familial Genome-Wide Haplotype Analysis Identified Five Novel Breast Cancer Susceptibility Loci on 9p24.3, 11q22.3, 15q11.2, 16q24.1 and Xq21.31
Open AccessArticle by Elin Barnekow 1,2,*, Johan Hasslow 2, Wen Liu 3,4, Patrick Bryant 3,5,6, Jessada Thutkawkorapin 3, Camilla Wendt 1,2, Kamila Czene 7, Per Hall 2,7, Sara Margolin 1,2 and Annika Lindblom 3,8,* 1 Department of Clinical Science and Education, Karolinska Institutet, 11883 Stockholm, Sweden 2 Department of Oncology, Södersjukhuset, 11883 Stockholm, Sweden 3 Department of Molecular Medicine and Surgery, Karolinska Institutet, 17176 Stockholm, Sweden 4 Department of...
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