Eliran Eitan

Nanopore sequencing has emerged as a powerful platform in genomics, offering the unique capability to read long nucleic acid molecules at the single-molecule level. (1−6) Protein nanopores function as ultrasensitive molecular sensors, that detect changes in ionic current as individual molecules traverse the pore. (6,7) When an applied voltage drives ionic current through the nanopore, the passage of a molecular species attenuates the flow, producing a measurable change in current.