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Elise Johanna Hingst on Muck Rack

Elise Johanna Hingst

As seen in: BioRxiv
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Articles

Competitive Adsorption of a Monoclonal Antibody and Amphiphilic Polymers to the Air-Water Interface

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By Michaela Blech, Dariush Hinderberger, Patrick Garidel, Elise Johanna Hingst
| BioRxiv
Abstract Understanding structure and self-organization of monoclonal antibodies (mAbs) at the air-water interface is important for the stability and effectiveness of protein drug formulations used in pharmaceutical industry. This paper investigates the competitive adsorption of a mAb and the amphiphilic surfactants poloxamer 188 (P188) and polysorbate 20 (PS20), both of which are commonly used to prevent mAb surface adsorption.
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