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Evaluating Activated Regulatory T Cells as a Biomarker of Chronic Allograft Inflammation in Pediatric Kidney Transplant Recipients
AR acute rejection aTreg activated regulatory T cell AUC area under curve BCCH British Columbia Children's Hospital BSA body surface area CI confidence interval ci interstitial fibrosis ct tubular atrophy DSA donor specific antibodies eGFR estimated glomerular filtration rate ESRD end-stage renal disease HLA human leukocyte antigen Ht height i interstitial inflammation IFTA interstitial fibrosis and tubular atrophy i-IFTA inflammation within areas of IFTA IL-17 interleukin 17 J Youden index...
Optimizing the approach to monitoring allograft inflammation using serial urinary CXCL10/creatinine testing in pediatric kidney transplant recipients
AUC area under the curve ALT alanine aminotransferase BCCH British Columbia Children's Hospital BK BK polyoma virus CMV cytomegalovirus CXCL10 chemokine (C-X-C motif) ligand 10 DAP Diagnostic Accreditation Program IFTA interstitial fibrosis and tubular atrophy IV intravenous IQR interquartile range PPV positive predictive value ROC receiver operating characteristic SR subclinical rejection uCXCL10/Cr urinary CXCL10/creatinine UTI urinary tract infection 1 INTRODUCTION Acute rejection is...
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