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Elli Kubarakos on Muck Rack

Elli Kubarakos

As seen in: Stem Cell Reports
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Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation

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By Rony Chidiac, Andy Yang, Nicholas Mikolajewicz, Maíra Almeida, Pierre E. Thibeault, Sichun Lin, Graham MacLeod, Jason Moffat, Stéphane Angers, Elli Kubarakos, Jean-Philippe Gratton
| Stem Cell Reports Verified
Keywords Wnt signaling human pluripotent stem cells mesoderm specification directed differentiation Wnt agonists Frizzled receptors Introduction During embryonic development, secreted growth factors govern the differentiation of human pluripotent stem cells (hPSCs) into specific cell types (Fowler et al., 2020). The magnitude and duration of intracellular signaling determine cell fate commitment. hPSCs are a tractable in vitro model to study how these signals influence cell differentiation.
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