Ellie J Tong on Muck Rack

Ellie J Tong

As seen in: Microbiology Research
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By Ellie J Tong, Kate A Bickerton, Alina J Creber, Robyn Manley
| Microbiology Research
Introduction . Acinetobacter baumannii is a critical priority pathogen for novel antimicrobials (World Health Organization) because of the rise in nosocomial infections and its ability to evolve resistance to last resort antibiotics. A. baumannii is thus a priority target for phage therapeutics. Two strains of a novel, virulent bacteriophage (LemonAid and Tonic) able to infect carbapenem-resistant A.
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Eliminating the type I restriction endonuclease from Pseudomonas aeruginosa PAO1 for optimized phage isolation

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By Ellie J Tong, Kate A Bickerton, Alina J Creber, Steven Porter
| Microbiology Research
Article metrics loading... /content/journal/micro/10.1099/mic.0.001634 Metrics Download as PowerPoint /deliver/fulltext/micro/171/11/mic001634.html?itemId=/content/journal/micro/10.1099/mic.0.001634&mimeType=html&fmt=ahah References Suetens C, Hopkins S, Kolman J, Diaz Högberg L. Point Prevalence Survey of Healthcare-Associated Infections and Antimicrobial Use in European Acute Care Hospitals Stockholm: ECDC; 2013 [View Article] [Google Scholar] Qin S, Xiao W, Zhou C, Pu Q, Deng X et al.
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Eliminating the type I restriction endonuclease from Pseudomonas aeruginosa PAO1 for optimised phage isolation

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By Steven Porter, Ellie J Tong, Kate A Bickerton, Alina J Creber
| biorxiv.org
Abstract Phage therapy is a promising treatment for multidrug-resistant bacterial infections. Due to their high host specificity, phages must be matched to the target clinical strains. Efficiently identifying appropriate phages and producing sufficient titres for clinical use requires comprehensive phage libraries and multiple propagation hosts. An idealised system would use a highly promiscuous bacterial host to isolate a broader range of phages and streamline optimised phage production.
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