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Emilie Barsac on Muck Rack

Emilie Barsac

As seen in: BioRxiv
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Articles

MAIT cells protect in severe pneumococcal pneumonia by regulating neutrophil/macrophage antimicrobial activities

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By Emilie Barsac, Loic Gonzalez, Antoine Hankard, Guy Ilango
| BioRxiv
Abstract Mucosal-Associated Invariant T (MAIT) cells populate the lung tissue where they contribute to defense against respiratory infections. While MAIT cells have been implicated in host resistance to infections caused by Gram-negative bacteria, their contribution in immunity against Gram-positive bacteria-driven pneumonia is still enigmatic.
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IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections

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By Youenn Jouan, Loic Gonzalez, Florent Creusat, Emilie Barsac
| BioRxiv
Abstract Neutrophil subsets endowed with regulatory/suppressive properties are widely regarded as deleterious immune cells that can jeopardize antitumoral response and/or antimicrobial resistance. Here, we describe a sizeable fraction of neutrophils characterized by the expression of Programmed death-ligand 1 (PD-L1) in biological fluids of humans and mice with severe viral respiratory infections (VRI).
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