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Emilio Eric Flint on Muck Rack

Emilio Eric Flint

As seen in: BioRxiv
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Articles

Targeting the expansion of myeloid-derived suppressor cells in liver cirrhosis

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By Caner Ercan, Eoin Mitchell, Emilio Eric Flint, Oltin Tiberiu Pop
| BioRxiv
Abstract Background and aims: Previously, we identified immune-suppressive circulating monocytic myeloid-derived suppressor cells (M-MDSC) in patients with cirrhosis and liver failure, which increased with disease severity and were associated with infections and mortality. Impaired immune responses and M-MDSC expansion were reversed by ex vivo polyinosinic:polycytidylic acid (poly(I:C)) treatment.
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