Emma Jenkinson

It’s 6:30 a.m. at Zuma Beach, along the Pacific Coast Highway in Malibu, and the sun is just starting to rise over the Santa Monica Mountains. Situated across the street from my old high school, this is, for me, familiar territory—but it’s in an all new context now, serving as the “Incident Command Post” for responders to the Palisades Fire.

Background and objective Postural Orthostatic Tachycardia Syndrome (POTS) is a chronic health condition affecting mostly women of childbearing age, and significantly impacting their health and quality of life. It is currently poorly understood with no approved licensed treatments. The aim of this systematic review was to contextualize the symptom burden of POTS, and review factors associated with this burden that may guide future treatments.