Key takeaways Pregabalin is used to treat acute anxiety, neuropathic pain, and seizures in cats. The standard pregabalin dosage for cats is 1–2 mg/kg given twice daily or 5 mg/kg given as a single dose for acute anxiety. The most common side effects of pregabalin in cats are tiredness, vomiting, sedation, and loss of coordination. Do not give pregabalin to cats who are allergic to the drug.