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Emmanuel Charles Kasule on Muck Rack

Emmanuel Charles Kasule

As seen in: PLOS ONE
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Articles

Burden of sickle cell anemia in Africa: A systematic review and meta-analysis

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By Bwambale Jonani, Emmanuel Charles Kasule, Bwire Roman Herman, Joel Fredrick Arturo
| PLOS ONE
Discussion This systematic review and meta-analysis provides a comprehensive synthesis of sickle cell anemia (SCA) prevalence due to HbSS across Africa, analyzing 115 studies encompassing nearly 1.2 million participants. We estimated a pooled prevalence of 1.43% (95% CI: 1.08%–1.88%), though this summary estimate must be interpreted cautiously given the extreme heterogeneity (I2 = 99.1%) and wide prediction interval (0.21%–8.91%), indicating substantial variation across populations and settings.
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Prevalence of sickle cell anemia in Africa: A protocol for a meta-analysis of existing studies

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By Wakiso District, Bwambale Jonani, Emmanuel Charles Kasule, Herman Roman Bwire
| PLOS ONE
Citation: Jonani B, Kasule EC, Bwire HR, Ricky O, Arturo JF, Livingstone M, et al. (2025) Prevalence of sickle cell anemia in Africa: A protocol for a meta-analysis of existing studies. PLoS ONE 20(4): e0321535. https://doi.org/10.1371/journal.pone.0321535 Editor: Santosh L. Saraf, University of Illinois at Chicago, UNITED STATES OF AMERICA Received: January 17, 2025; Accepted: March 8, 2025; Published: April 21, 2025 Copyright: © 2025 Jonani et al.
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