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Emmely A. Patrasso on Muck Rack

Emmely A. Patrasso

As seen in: Nature
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Articles

The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferation

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By Mahmood H. Dalhat, Sharath Narayan, Maria Eleftheriou, James Russell, James R. Heslop, Hannah Serio, Evangelia Stamou, Judith Lopez, Demetrios Aspris, Stephanie Mou, George Giotopoulos, Walid T. Khaled, Brian J. P. Huntly, Fotios Sampaziotis, Konstantinos Tzelepis, Daniel Arango, Khulood A. Alzahrani, Adam Suh, Ajay Edakkara, Sweta Raikundalia, Lea Landmann, Ryan Asby, Yogeshkumar Malam, Emmely A. Patrasso
| Nature Verified
Abstract N-acetyltransferase 10 (NAT10) is a multifunctional enzyme that harbors RNA acetyltransferase and RNA helicase domains and has emerged as a therapeutic vulnerability in solid and hematological malignancies.
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