Emrah Yatkin on Muck Rack

Emrah Yatkin

As seen in: Journal of Nuclear Medicine
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Articles

Preclinical Evaluation of 89Zr-Desferrioxamine-Bexmarilimab, a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, in a Rabbit Model of Renal Fibrosis

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By Olli Moisio, Jenni Virta, Heidi Liljenbäck, Emrah Yatkin
| Journal of Nuclear Medicine Verified
Abstract Bexmarilimab is a new humanized monoclonal antibody against common lymphatic endothelial and vascular endothelial receptor-1 (CLEVER-1) and is in clinical trials for macrophage-guided cancer immunotherapy. In addition being associated with cancer, CLEVER-1 is also associated with fibrosis. To facilitate prospective human PET studies, we preclinically evaluated 89Zr-labeled bexmarilimab in rabbits.
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