Emranul Karim on Muck Rack

Emranul Karim

As seen in: Taylor & Francis Online
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Articles

Modified Sodium Caseinate-based Nanomicelles for Enhanced Chemotherapeutics Against Breast Cancer via Improved Cellular Uptake and Cytotoxicity

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By Farah Rehan, Nafees Ahemad, Omer Salman Qureshi, Emranul Karim
| Taylor & Francis Online
Abstract Objective Poor prognosis, drug resistance, and lower drug loading capacity of the delivery systems lead to therapeutic failures of breast cancers. Herein we functionalized sodium caseinate nanomicelles (NaCNs) with the divalent calcium (Ca2+) and the glucose (Glc) to increase the loading capacity of micelles for higher cellular uptake and cytotoxicity against breast cancer cells. Methodology Modification of casein micelles was confirmed through Fourier Transform Infrared Spectra (FTIR).
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