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Articles by En Ren
Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy
Keywords drug delivery cell therapy mast cells oncolytic adenoviruses cell-drug conjugate cancer immunotherapy Get full text access Log in, subscribe or purchase for full access. References 1. Vargason, A.M. ∙ Anselmo, A.C. ∙ Mitragotri, S. The evolution of commercial drug delivery technologies Nat. Biomed. Eng. 2021; 5:951-967 2. Lim, W.A. The emerging era of cell engineering: Harnessing the modularity of cells to program complex biological function Science. 2022; 378:848-852 3. Chen, Z. ∙ Hu, Q. ∙ Gu, Z.
Water‐Stable Magnetic Lipiodol Micro‐Droplets as a Miniaturized Robotic Tool for Drug Delivery
Conflict of Interest The authors declare no conflict of interest.
Ruthenium‐Based Metal-Organic Nanoradiosensitizers Enhance Radiotherapy by Combining ROS Generation and CO Gas Release
Abstract A multifunctional X-ray reactor, ZrRuMn-MONs@mem, was developed to enhance radiotherapy by combining ROS generation and CO gas release. The well-designed nanostructures can increase the direct absorption of radiation doses (primary radiation) and promote the deposition of photons and electrons (secondary radiation). Furthermore, the coating of the targeting cell membrane improved this radiosensitizer with a certain degree of targeting and biocompatibility.
Surface engineering of oncolytic adenovirus for combinations of immune checkpoint blockade and virotherapy
Surface engineering of oncolytic adenovirus for combinations of immune checkpoint blockade and virotherapy Advances in the development of modern cancer immunotherapy and immune checkpoint inhibitors have dramatically changed the landscape of cancer treatment. However, most cancer patients are refractory to immune checkpoint inhibitors because of low lymphocytic tumor infiltration and PD-L1 expression.
Zinc(II)‐Dipicolylamine Coordination Nanotheranostics: Toward Synergistic Nanomedicine by Combined Photo/Gene Therapy
Abstract We report the rational design of coordination‐driven self‐assembly metal–organic nanostructures for multifunctional nanotheranostics. Zinc(II) coordination‐based nano‐formulations capable of loading indocyanine green (ICG) and therapeutic genes were prepared to achieve a fluorescence/photoacoustic imaging‐guided combination photo/gene therapy strategy.
Zinc(II)‐dipicolylamine Coordination Nanotheranostics: Toward Synergistic Nanomedicine by Combined Photo/gene Therapy
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