Enid C. Ibarra

Abstract Urinary tract infections (UTIs) are highly recurrent and frequently caused by Uropathogenic Escherichia coli (UPEC) strains that can be found in patient intestines. Seeding of the urinary tract from this intestinal reservoir likely contributes to UTI recurrence (rUTI) rates. Thus, understanding the factors that promote UPEC intestinal colonization is of critical importance to designing therapeutics to reduce rUTI incidence. Although E.

Bacterial motility, not phagocyte motility, drives outcomes in the L-CPM The finding that neutrophils are recruited to the apical side of the epithelium following Lm infection suggests that they might have a protective function in clearing bacteria at the luminal surface during ongoing infections. However, it remains unclear how important these interactions are for preventing further bacterial invasion—or how Lm motility affects these host-pathogen interactions at the epithelium.