Strategic Director of Pharmacoepidemiology for the American Cancer Society
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Articles by Eric J. Jacobs
A Large Cohort Study of Body Mass Index and Pancreatic Cancer by Smoking Status
Research Articles Eric J. Jacobs, Christina C. Newton, Victoria L. Stevens, Alpa V. Patel, W. Dana Flanders and Susan M. Gapstur DOI: 10.1158/1055-9965.EPI-20-0591 Published December 2020 This article requires a subscription to view the full text. You may purchase access to this article or login to access your subscription using the links below.
A Large Cohort Study of Body Mass Index and Pancreatic Cancer by Smoking Status
Research Article Eric J. Jacobs, Christina C. Newton, Victoria L. Stevens, Alpa V. Patel, W. Dana Flanders and Susan M. Gapstur DOI: 10.1158/1055-9965.EPI-20-0591 Abstract Background: Some evidence suggests the association between body mass index (BMI) and pancreatic cancer risk is weaker among current smokers than among never smokers.
A Large Cohort Study of Body Mass Index and Pancreatic Cancer by Smoking Status
Research Article Eric J Jacobs, Christina C. Newton, Victoria L. Stevens, Alpa V. Patel, W. Dana Flanders and Susan M. Gapstur DOI: 10.1158/1055-9965.EPI-20-0591 Abstract Background: Some evidence suggests the association between BMI and pancreatic cancer risk is weaker among current smokers than among never smokers.
The Association Between Body Mass Index and Pancreatic Cancer
Abstract and Introduction Abstract Higher body mass index (BMI; weight (kg)/height (m)2) is associated with increased risk of pancreatic cancer in epidemiologic studies. However, BMI has usually been assessed at older ages, potentially underestimating the full impact of excess weight. We examined the association between BMI and pancreatic cancer mortality among 963,317 adults who were aged 30–89 years at their enrollment in Cancer Prevention Study II in 1982.
Red and Processed Meat, Poultry, Fish, and Egg Intakes and Cause-Specific and All-Cause Mortality among Men with Nonmetastatic Prostate Cancer in a U.S. Cohort
Research Articles Ying Wang, Eric J. Jacobs, Roma A. Shah, Victoria L. Stevens, Ted Gansler and Marjorie L. McCullough DOI: 10.1158/1055-9965.EPI-19-1426 Published May 2020 Abstract Background: Research on the relationship of meat, fish, and egg consumption and mortality among prostate cancer survivors is limited. Methods: In the Cancer Prevention Study-II Nutrition Cohort, men diagnosed with nonmetastatic prostate cancer between baseline in 1992/1993 and 2015 were followed for mortality until 2016.
Postdiagnosis Body Mass Index, Weight Change, and Mortality From Prostate Cancer, Cardiovascular Disease, and All Causes Among Survivors of Nonmetastatic Prostate Cancer | Journal of Clinical Oncology
To investigate the association of postdiagnosis body mass index (BMI) and weight change with prostate cancer–specific mortality (PCSM), cardiovascular disease–related mortality (CVDM), and all-cause mortality among survivors of nonmetastatic prostate cancer. Men in the Cancer Prevention Study II Nutrition Cohort diagnosed with nonmetastatic prostate cancer between 1992 and 2013 were followed for mortality through December 2016.
Excess body weight earlier in life may have greater influence on pancreatic cancer mortality risk
ATLANTA — Excess body weight before age 50 years may increase pancreatic cancer mortality risk to a greater degree than excess weight at older ages, according to results from the Cancer Prevention Study II presented at American Association for Cancer Research Annual Meeting. “Pancreatic cancer rates have been steadily increasing since the early 2000s,” Eric J. Jacobs, PhD, senior scientific director of epidemiology research at American Cancer Society, said in a press release.
Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults
In this first large comprehensive human study, we observed that overall microbiome community composition in the oral cavity differed by drinking level, with consistent results across two independent cohorts and after exclusion of current smokers. Drinkers had decreased abundance of order Lactobacillales, the major order in the Firmicutes phylum. Other taxa, some of which are potentially pathogenic, were enriched with higher alcohol consumption.
Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study
We conducted a prospective study nested in two large US cohorts, the American Cancer Society Cancer Prevention Study (CPS) II and the National Cancer Institute Prostate, Lung, Colorectal and Ovarian Cancer (PLCO) Screening Trial, to determine if oral microbiome was associated with subsequent risk of pancreatic cancer.
Why Epidemiological Studies of Physical Activity in Prostate Cancer Often Underestimate its Benefits
Reply to Parham Habibzadeh and Farrokh Habibzadeh's Letter to the Editor re: Eric A. Klein, Arnon Chait, Jason M. Hafron, et al. The Single-parameter, Structure-based IsoPSA Assay Demonstrates Improved Diagnostic Accuracy for Detection of Any Prostate Cancer and High-grade Prostate Cancer Compared to a Concentration-based Assay of Total Prostate-specific Antigen: A Preliminary Report. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2017.03.025.
Recreational Physical Activity in Relation to Prostate Cancer-specific Mortality Among Men with Nonmetastatic Prostate Cancer
In this large prospective cohort study of men diagnosed with nonmetastatic prostate cancer, higher prediagnosis recreational PA (?17.5 MET-h/wk or 5?h of moderate-intensity activity per week), including walking, was associated with a lower risk of PCSM among men with lower-risk tumors but not among men with high-risk tumors.
Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study
Objective A history of periodontal disease and the presence of circulating antibodies to selected oral pathogens have been associated with increased risk of pancreatic cancer; however, direct relationships of oral microbes with pancreatic cancer have not been evaluated in prospective studies. We examine the relationship of oral microbiota with subsequent risk of pancreatic cancer in a large nested case–control study.
Calcium intake and mortality from all causes, cancer, and cardiovascular disease: the Cancer Prevention Study II Nutrition Cohort
Background: Calcium intake may be important for bone health, but its effects on other outcomes, including cardiovascular disease (CVD) and cancer, remain unclear. Recent reports of adverse cardiovascular effects of supplemental calcium have raised concerns. Objective: We investigated associations of supplemental, dietary, and total calcium intakes with all-cause, CVD-specific, and cancer-specific mortality in a large, prospective cohort.
Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants
Importance Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with lower risk of colorectal cancer. Objective To identify common genetic markers that may confer differential benefit from aspirin or NSAID chemoprevention, we tested gene × environment interactions between regular use of aspirin and/or NSAIDs and single-nucleotide polymorphisms (SNPs) in relation to risk of colorectal cancer.
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