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EaMIC3 inhibits cell apoptosis and facilitates Eimeria acervulina infection through interacting with EpCAM
Abstract Coccidiosis, caused by Eimeria acervulina, is a pathogenic protozoan disease, leading to huge economic losses to the global poultry industry. At the early stage of E. acervulina infection, microneme protein 3 (EaMIC3) is involved in the inhibition of infected host cell apoptosis, but the underlying mechanisms remain unclear. Here, EaMIC3 was shown to inhibit the apoptosis of infected host cells and facilitate parasite infection by interacting with epithelial cell adhesion molecule (EpCAM).
Author Correction: Mapping self-associating chromatin hubs identifies Id proteins as key determinants of exhausted CD8 + T cell fate
Correction to: Nature Immunology https://doi.org/10.1038/s41590-026-02578-4, published online 6 July 2026. In the version of the article initially published, in the “Under RNA-seq and data analyses” section of the Methods, the last sentence of the “Data generation” paragraph was “The RNA-seq FASTQ files of CD8+ TN cells were previously reported and deposited at the GEO (GSE164712)” but should have been “The RNA-seq data of CD8+ TN cells were newly generated and deposited at the GEO (GSE343749)”.
BBOX1 Deficiency Exacerbates Liver Fibrosis Through Carnitine Biosynthesis Disruption Rescued by Carnitine Supplementation
Handling Editor: Luca Valenti Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The raw sequence data of RNA were deposited in the NCBI SRA database with the accession number of PRJNA1217840. The authors confirm that the data supporting the findings of this study are available within the article. Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon request (Yu Gao, gaoyu@bbmu.edu.cn).
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