CL, ELC, JW, SPK, QL, KLD, MML, BDG and EB are employees of Pfizer and may hold stock or stock options. JAL has received research grants, honoraria, and speaker fees from Pfizer Inc. for related/unrelated work; research grants and honoraria from Merck, Sharp, & Dohme for unrelated work; honoraria from Valneva for unrelated work; consulting fees from Seqirus Inc. for unrelated work; and honoraria from VaxCyte for unrelated work. This study was funded by Pfizer Inc.