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To the Editor: Oral isotretinoin has been used for decades to treat moderate to severe recalcitrant nodulocystic acne. 1 Tan T.H. Hallett R. Yesudian P.D. Efficacy and relapse rates of different Isotretinoin dosages in treating acne vulgaris: systemic review. Clin Med (Lond). 2016; 16: s34 One way to evaluate the effectiveness of treatments is to measure relapse rates after treatment completion.
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