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Ernst-Wilhelm Radue on Muck Rack

Ernst-Wilhelm Radue

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Articles

Association of brain volume loss and long-term disability outcomes in patients with multiple sclerosis treated with teriflunomide

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By Till Sprenger, Ludwig Kappos, Ernst-Wilhelm Radue, Laura Gaetano
| SAGE Publishing
Introduction Brain volume loss (BVL) is accelerated in patients with MS and occurs early in the disease course.
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Defining brain volume cutoffs to identify clinically relevant atrophy in RRMS

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By Maria Pia Sormani, Ludwig Kappos, Jeffrey A Cohen, Ernst-Wilhelm Radue
| SAGE Publishing
To define values of normalized brain volume (NBV) that can be categorized as low, medium, or high, according to baseline characteristics of relapsing-remitting multiple sclerosis (RRMS) patients. Expected NBV (eNBV) was calculated for each patient based on age, disease duration, sex, baseline Expanded Disability Status Scale (EDSS), and T2-lesion volume, entering these variables into a multiple regression model run on 2342 RRMS patients (pooled FREEDOMS/FREEDOMS-II population).
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